Which of the following is the most appropriate therapeutic approach at this point?
Initiate a course of plasma exchange and then observe; start azathioprine if a clinical relapse occurs.
Start immunosuppression with azathioprine and continue it until AQP4-IgG is no longer detectable in serum.
No additional therapy is indicated now; treat future clinical relapses as need with corticosteroids.
Start immunosuppressive therapy with azathioprine; if a breakthrough attack occurs, switch to natalizumab.
Start long-term immunosuppressive therapy with rituximab.
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