Most heartbreaking moment

• Mary telling Dean that she never wants her kids to be Hunters

• Dean telling Mary not to get out of bed on November 3, 1983

• Mary kissing Samuel (ew!) and making the deal to bring John back -- she doesn't know she's dooming her family!

• Dean mourning that he couldn't change anything... and Castiel telling him he never would have been able to, anyway. How could he!